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Mutated Spiders are a deadlier variety of Small Spider and are found in Watcher's Keep and Sendai's Lair.

Mutated Spiders have a two hit points less compared to small spiders but they have a permanent Normal Haste effect active and a higher number of attacks per turn. And unlike small spiders, they can deliver a lethal dose of poison to their target creature upon a successful hit. Like all spiders they are immune to Web.

They are usually encountered in decent numbers and because of their increased movement speed, it is best to kill them quickly. Spells such as Entangle, Grease, Slow and Hold Animal or a Wands of Paralyzation may help to slow them down.

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The Sword Coast Stratagems assigns revised default AI scripts to guide their attack targeting and other combat behavior, which is more responsive to their enemies' protections and recognized vulnerabilities. They'll look for targets unprotected from Poison as a priority.

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